Risk and Prognostic Factors of Inpatient Mortality Associated with Unintentional Insecticide and Herbicide Poisonings: A Retrospective Cohort Study
نویسندگان
چکیده
INTRODUCTION Pesticide poisoning is an important public health problem worldwide. The study aimed to determine the risk of all-cause and cause-specific inpatient mortality and to identify prognostic factors for inpatient mortality associated with unintentional insecticide and herbicide pesticide poisonings. METHODS We performed a retrospective cohort study of 3,986 inpatients recruited at hospitalization between 1999 and 2008 in Taiwan. We used the International Classification of Disease, 9th ed., Clinical Modification external causes of injury codes to classify poisoning agents into accidental poisoning by insecticides and herbicides. Comparisons in mortality rates were made between insecticide poisoning patients and herbicide poisoning patients by using the Cox proportional hazards models to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs). RESULTS There were 168 deaths during 21,583 person-days of follow-up evaluation (7.8 per 1,000 person-days). The major causes of mortality for insecticide poisonings were the toxic effect of organophosphate and coma, and the major causes of mortality for herbicide poisonings were the toxic effect of other pesticides and the toxic effect of organophosphate. The mortality for herbicide exposure was fourfold higher than that for insecticide exposure. The factors associated with inpatient mortality were herbicide poisonings (HR = 4.58, 95% CI 3.29 to 6.37) and receiving mechanical ventilation treatment (HR = 3.85, 95% CI 2.73 to 5.42). CONCLUSIONS We demonstrated that herbicides stand out as the dominant agent for poisoning-related fatalities. The control of and limiting access to herbicide agents and developing appropriate therapeutic regimens, including emergency care, should be priorities.
منابع مشابه
Inpatient Mortality Following Repair of Abdominal Aortic Aneurysm in a Tertiary Hospital in Tehran
This study was conducted to monitor the rate of inpatient mortality and its associated factors following open reconstruction of abdominal aortic aneurysm (AAA) in a tertiary hospital in Tehran, Iran. This retrospective study was a chart review of 112 patients undergoing open in­frarenal abdominal aortic aneurysm surgery in one of the main tertiary hospitals in Tehran, Iran. Baseline data (d...
متن کاملFactors Associated with Incidence and Severity of Acute Poisoning in Aged People: A Retrospective Cross-Sectional Study in North of Iran, 2013-2020
Background and purpose: Mortality rate due to intentional and unintentional poisoning is higher in vulnerable older adults than the general population. This study was performed to determine the prevalence of acute poisoning and factors associated with the incidence and severity of this condition in aged people. Materials and methods: A retrospective cross-sectional study was conducted using t...
متن کاملA case-control study on risk factors for unintentional childhood poisoning in Tehran
Background: Poisoning is a major public health problem and is one of the most frequent causes of emergency hospital admissions. The aim of this study was to identify the main risk factors for unintentional childhood poisoning in Tehran, Iran and to suggest possible causes and preventative measures. Methods: In this case-control study (case, n=140; control, n=280), two controls were se...
متن کاملRisk Factors and Prognostic Factors of Acute Renal Failure in Patients Admitted to an Intensive Care Unit, Tehran-Iran
Acute renal failure (ARF) is defined as a sudden and continuous decrease of glomerular function associated with azotemia, and may be followed by decreased urinary output. There is a high incidence of ARF in ICU patients with a high mortality rate. Many factors can promote ARF development or influence its outcome. This study was done to assess the incidence, risk factors, outcome and treatme...
متن کاملA Hospital-Based Epidemiologic Study on Acute Pediatric Poisonings in Chennai, India
Background: Toxic exposures in childhood are major health concern. In this hospital-based study, we sought to investigate socio-epidemiological factors contributing to acute pediatric poisoning in Chennai, Tamil Nadu, India. Methods: This prospective cross-sectional study was conducted at the Kanchi Kamakoti CHILDS Trust Hospital (KKCTH), a tertiary care hospital for children in Chennai. Child...
متن کامل